BERBAMINE SUPPRESSES INTESTINAL SARS-COV-2 INFECTION VIA A BNIP3-DEPENDENT AUTOPHAGY BLOCKADE



The role of extended resection in locally recurrent colorectal cancer with invasion of the aortoiliac bifurcation: a rare clinical case

Colorectal carcinoma (CRC) is the third most common cancer and the fourth deadliest.Despite recent advances in screening methods and preoperative imaging techniques, the threat of colorectal cancer remains at an all-time Hat high.Moreover, even after curative treatment, disease recurrence occurs in up to 40% of all cases.However, half of patients w

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Gain-of-function, focal segmental glomerulosclerosis Trpc6 mutation minimally affects susceptibility to renal injury in several mouse models

Mutations in TRPC6 are a cause of autosomal dominant focal segmental glomerulosclerosis in humans.Many of these mutations are known to have a gain-of-function effect on the non-specific cation channel function Modified Citrus Pectin of TRPC6.In vitro studies have suggested these mutations affect several signaling pathways, but in vivo studies have

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